1. Project Overview

Tendering Entity: Beijing Minhai Biotechnology Co., Ltd.

Project Name: Minhai Biologics New‑Type Vaccine International Industrial Base Construction Project – 1 Supply and Installation of Laboratory Furniture for the R&D Pilot-Scale Workshop

Project Address: No. 35, Simiao Road, Biomedical Industry Base, Daxing District, Beijing Number

Project Overview: The Minhai Biologics International Vaccine Industrial Base Project, invested in and constructed by Beijing Minhai Biotechnology Co., Ltd., is located at Plot 0503-039 within the Daxing Biopharmaceutical Industry Base. Plots 040, 043, and 044 are bounded as follows: to the north by Simiao Road; to the south by the planned land‑use boundary (municipal green space); to the west by Xiangrui Avenue; and to the east by Tianfu Avenue. The project is primarily intended for the research, development, and production of human vaccines.

1 Building No. ___ Construction Scale: Building footprint area 7,588.48 m² ² , with a total floor area of 53,119.36 m² ² The building has a height of 31.80 meters, with one basement level and six above-ground floors. The basement floor-to-floor height is 6.6 meters; the first through third floors are 4.5 meters high; the fourth and fifth floors are 6.0 meters high; and the sixth floor is 4.5 meters high.

Supporting utility systems:

l The power source comes from 1. The substation is designed and constructed separately by the power authority.

l Drinking water is supplied by the basement softening water treatment plant, while process water is sourced from 4. The water‑treatment stations are designed and constructed separately by the wastewater‑treatment and process‑water units.

l Hot water, chilled water, and process chilled water are supplied by chillers installed at the basement power station; equipment specifications shall be provided by the design institute.

l Industrial steam is supplied by the plant’s steam boiler and requires parameters to be provided by the design institute.

l Activated wastewater is collected centrally in the basement and routed to the waste‑liquid inactivation unit; after treatment, it is discharged into the municipal sewage network.

l Ordinary wastewater is discharged directly into the sewage network.

II. Scope of Tender

1. It is necessary to conduct a second verification of the drawings and equipment specifications provided by Party A, and to perform any required secondary optimization design as needed.

2. The overall scope of the tender for this project is 1# Second floor of the R&D and pilot-scale workshop ( PI Laboratory 1 ~ 16 ) , third floor ( PI Laboratory 1 ~ 16 ), four floors ( Research Laboratory 1 ~ 8 , Experimental Platform I, Formulation Platform, Genetic Engineering Experimental Platform, Refrigerator Room, and Material Storage Room 3) , Sixth floor (including: pre-processing room, the… 1 ~ 5 Laboratory, Stability Testing Area and Archives, Biochemical Laboratory 1 ~ 3 , Physical and Chemical Laboratory 1 , Chromatography Room 1 ~ 3 ) of laboratory space and associated functional rooms, with a laboratory area of approximately 12000 Square meters (the exact area shall be subject to the final tender drawings and bill of quantities).

3. The scope of construction includes: except Furniture supply, installation of load-bearing suspended ceilings, and installation of associated MEP systems for all laboratory areas outside the scope of fit-out, MEP works, and cleanroom engineering. Includes the aforementioned areas: ceiling construction and laboratory furniture supply, office furniture supply, electrical engineering, plumbing and drainage, low-voltage and intelligent systems, HVAC and power engineering, smoke extraction and make-up air systems, process piping works, and gas leak detection; also encompasses the supply, installation, commissioning, acceptance, and validation of related equipment such as air-conditioning units, exhaust fans, fume hoods, reagent cabinets, pipelines, ductwork, valves, and more. Coordination with the client is required for laboratory-related activities. CNAS Certify and provide the relevant documentation.

4. BIM modeling for MEP installations is required for all laboratories. Design.

5. Seamlessly coordinate with all participating construction entities, including Party A’s designated general contractor for fit-out works, purification systems, flooring, MEP systems, and fire protection, to ensure the project is completed on schedule, to the required quality standards, and in accordance with the specified scope.

6. Planned construction period: 2021 June 1, 2021 – December 31, 2021.

3. Quality Standards

This project is a key initiative of Beijing Municipality, and its construction approach must meet the following requirements: scientific rigor, human-centered design, standardization, intelligent technology, and landscape integration, with an unwavering commitment to achieving Level 5. The overarching goal is to remain at the forefront within the year and to avoid falling behind within ten years.

The project must comply with the relevant laws and regulations of China, the European Union, the United States, and the World Health Organization pertaining to laboratories and pharmaceutical pilot-scale manufacturing facilities; it must also meet fire safety requirements and occupational health and safety standards.

Including, but not limited to, the requirements of the following current editions of standards:

Good Manufacturing Practice for Pharmaceuticals ( 2010 (Revised in [Year]) and its appendices

Pharmaceuticals GMP Guide - Factory Buildings and Equipment

Code for Design of Cleanroom Engineering in the Pharmaceutical Industry GB50457

Code for Construction and Acceptance of Cleanrooms GB50591

Code for Construction and Acceptance of Architectural Decoration Projects JGJ73

Code for Construction and Acceptance of Ventilation and Air-Conditioning Engineering GB50243

Code for Construction and Acceptance of Industrial Metal Structure Engineering GB50235

Code for Fire Protection in Building Design GB50016

Code for Fire Protection of Interior Decoration in Buildings GB50222

Test Method for Suspended Particles in Cleanrooms (Clean Zones) of the Pharmaceutical Industry GB/T16292

“Test Method for Suspended Microorganisms in Cleanrooms (Areas) of the Pharmaceutical Industry” GB/T16293

“Test Method for Settling Microorganisms in Cleanrooms (Areas) of the Pharmaceutical Industry” GB/T16294

International Standard for Cleanrooms and Related Controlled Environments ISO 14644

High-Efficiency Air Filter GB/T13554

“Regulations on Automated Management of Pharmaceutical Production” GAMP5

Code for Construction and Acceptance of Industrial Automation Instrumentation Projects GB50093

Standard for Quality Inspection and Evaluation of Electrical Installation Works in Buildings GBJ303

Code for Quality Acceptance of Low-Voltage Electrical Apparatus Construction in Electrical Installation Projects GB50245

Code for Quality Acceptance of Electrical Engineering in Buildings GB50303

Code for Construction and Acceptance of Cable Lines in Electrical Installation Projects GB50168

Code for Construction and Acceptance of Earthing Works in Electrical Installation Projects GB50169

General Technical Requirements for Packaging of Mechanical and Electrical Products GB/T13384

“Code for Construction and Acceptance of Electrical Lighting Installations in Electrical Installation Projects” GB50259

Relevant regulations, safety standards, quality guidelines, energy‑saving requirements, and other documents issued by the local construction commission.

4. Registration Instructions:

1. Participating organizations must submit the following documents: the business license of the legal entity, qualification certificates, a certificate of the legal representative or a letter of authorization from the legal entity, and a copy of the legal representative’s ID card. All copies must bear the official seal of the organization, and the company’s registered capital must be clearly indicated.

2. Minimum qualification requirements:

l Second-class professional contracting for architectural decoration projects;

l Second-class professional contracting for architectural electromechanical engineering;

3. Participating registration units in the past 3 The following performance records are required for the years 2018, 2019, and 2020. And provide renderings and animated walkthroughs of the aforementioned project. ：

l Design of central laboratories for national and provincial-level public institutions, BSL-2/ABSL-2 , BSL-3/ABSL-3 laboratory construction contracting.

l National, provincial/ministerial-level, or Fortune Global 500 Construction contracting for the company’s biochemical, physicochemical, and biosafety laboratories.

l Top 10 in China’s pharmaceutical industry Construction contracting for advanced biochemical, physicochemical, and biosafety laboratories.

4.   Registration requires providing the organization’s contact person and contact information; the contact person must be the project leader or an designated business liaison, and please provide 12. Monthly social security certificate.

5. The tendering entity will review the qualification documents of registered entities, giving priority to those with relevant project experience, and will conduct further communication and on-site inspections with the shortlisted candidates.

6. Beijing Minhai Biotechnology Co., Ltd. was established in 2004. Year is a wholly owned subsidiary of Shenzhen Kangtai Biological Products Co., Ltd. (a publicly listed company). For more information, please visit the company’s website.

V. Registration Address:

Beijing Minhai Biotechnology Co., Ltd. (No. 35, Simiao Road, Bio‑Pharmaceutical Industry Base, Daxing District, Beijing) No.). Contact: Mr. Ba, New Engineering Project Department; Contact Phone: 15100657208; Email: mhzb@biominhai.com , three copies of the cardboard registration documents.

VI. Registration Deadline: 2021 May 16, 2023, at 17:30.

Hereby announced!

Tendering Entity: Beijing Minhai Biotechnology Co., Ltd.

                        2021 Year 04 28th of the month