Influenza and pertussis vaccines administered during pregnancy are likely to be safe for the infant.

Release date:

2018-03-30

Author:

Excerpt: BioValley

Source:

Excerpt: BioValley


Abstract

According to a February 21 report in the U.S. journal The Scientist, researchers recently published a study in the monthly Journal of Pediatrics examining more than 400,000 infants. The findings indicate that influenza and pertussis vaccination during pregnancy is safe. Among mothers who received these vaccines during pregnancy, the rates of hospitalization and mortality in their infants during the first six months after birth were not higher than those observed among infants born to unvaccinated mothers.

  According to a February 21 report in the U.S. journal The Scientist, researchers recently published a study in the monthly Journal of Pediatrics examining more than 400,000 infants. The study found that influenza and pertussis vaccinations administered during pregnancy are safe. Among infants born to mothers who received these vaccines during pregnancy, hospitalization and mortality rates during the first six months after birth did not exceed those of infants born to unvaccinated mothers.

  According to reports, Annette Regan, a public health researcher at Curtin University in Australia, told Reuters by email: “The fact that researchers found no evidence that vaccination during pregnancy causes serious harm to infants in the first six months after birth is reassuring. While other studies have examined infant hospitalizations, this is the first study to assess the impact on infant mortality.”

  According to the report, public health officials recommend that pregnant women receive both the influenza vaccine and the Tdap vaccine (tetanus–diphtheria–acellular pertussis). In this study, researchers analyzed the medical records of 413,000 infants collected from multiple healthcare systems. Although more than 25,000 infants were hospitalized before the age of six months and 157 infants died, the researchers found no significant association between these outcomes and maternal vaccination.

  The researchers wrote in their report: “Evidence is mounting that vaccination during pregnancy poses no long-term harm to infants, and our study helps to strengthen this evidence.”

  According to reports, researchers did find an association between the Tdap vaccine and hospitalization: infants whose mothers were not vaccinated with Tdap during pregnancy faced a higher risk of respiratory complications. The researchers noted that only 3% of infants were hospitalized for pertussis. They stated in their report: “This may suggest that children with pertussis were not adequately diagnosed or tested, and other factors—such as the healthy‑worker effect and additional differences between those who received the vaccine and those who did not—could also have contributed to this finding.”

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